The Vaginal Microbiome

The vaginal microbiome plays an important role in women’s health. If disrupted, recurrent infections such as bacterial vaginosis and vaginal candidiasis (yeast infection) are increasingly possible. Using metagenomic DNA sequencing, we are able to provide the community state type (which species of bacteria are dominant, if any), a complete microbiome profile, and indicators of vaginal wellness or dysbiosis.


The healthy vaginal microbiome is characterized by low microbial diversity and lactobacilli dominance, helping keep the vagina acidic. An increase of unwanted microbes can result in imbalance in the vaginal microbiome, causing discomfort and possible risks.

Lactobacilli is a genus of bacteria which produces lactic acid. Lactic acid prevents the increase of unwanted microbes, therefore helping balance the vaginal microbiome.

Understanding the makeup of your vaginal microbiome is one step towards rebalancing its environment, likely avoiding further dysbiosis.

Why care about the vaginal microbiome?

Vaginal health is important, especially since disruption in the environment can cause recurrent infections. Unhealthy microbiome risks include:

  • Bacterial vaginosis is caused by imbalance in the vagina as a result of bacteria overgrowth. BV is a type of vaginal inflammation that may cause symptoms including abnormal discharge, itching, or odor.

  • Yeast infections are commonly with the fungus candida (vaginal candidiasis), and can cause inflammation, itchiness, and abnormal discharge. Infections occur when candida yeast becomes out of balance at the opening of the vagina.

  • With a less acidic vaginal pH, women have an increased risk of contracting Sexually Transmitted Infections (STIs). An acidic environment is defense against unwanted bacteria and bacterial growth.

  • A disrupted vaginal microbiome can affect pregnancies, including preterm birth. Developing bacterial vaginosis during pregnancy also increases complication risks.

Benefits of Personal Testing

Answer questions about your microbiome:

  • How much of each organism is present? (relative abundance)

  • How many different organisms are present? (alpha diversity)

  • How dissimilar are samples when compared to each other? (beta diversity)

  • What organisms indicate wellness or dysbiosis?


With NirvanaBiome:

  • Convenient, easy-to-use kits

  • Assess your community state type

  • Monitor your microbiome over time

  • Take baseline tests when feeling good

  • Ability to look at polymicrobial view

  • Push research forward